Recalibration of the limiting antigen avidity EIA to determine mean duration of recent infection in divergent HIV-1 subtypes.
Identifieur interne : 000280 ( Main/Exploration ); précédent : 000279; suivant : 000281Recalibration of the limiting antigen avidity EIA to determine mean duration of recent infection in divergent HIV-1 subtypes.
Auteurs : Yen T. Duong [États-Unis] ; Reshma Kassanjee [Afrique du Sud] ; Alex Welte [Afrique du Sud] ; Meade Morgan [États-Unis] ; Anindya De [États-Unis] ; Trudy Dobbs [États-Unis] ; Erin Rottinghaus [États-Unis] ; John Nkengasong [États-Unis] ; Marcel E. Curlin [Thaïlande] ; Chonticha Kittinunvorakoon [Thaïlande] ; Boonyos Raengsakulrach [Thaïlande] ; Michael Martin [Thaïlande] ; Kachit Choopanya [Thaïlande] ; Suphak Vanichseni [Thaïlande] ; Yan Jiang [République populaire de Chine] ; Maofeng Qiu [République populaire de Chine] ; Haiying Yu [République populaire de Chine] ; Yan Hao [République populaire de Chine] ; Neha Shah [États-Unis] ; Linh-Vi Le [Viêt Nam] ; Andrea A. Kim [Kenya] ; Tuan Anh Nguyen [Viêt Nam] ; William Ampofo [Ghana] ; Bharat S. Parekh [États-Unis]Source :
- PloS one [ 1932-6203 ] ; 2015.
Descripteurs français
- KwdFr :
- Affinité des anticorps, Antigènes du VIH (immunologie), Calibrage, Humains, Séropositivité VIH (diagnostic), Séropositivité VIH (épidémiologie), Techniques immunoenzymatiques (normes), Tests sérologiques (normes), VIH-1 (Virus de l'Immunodéficience Humaine de type 1) (), VIH-1 (Virus de l'Immunodéficience Humaine de type 1) (génétique), VIH-1 (Virus de l'Immunodéficience Humaine de type 1) (immunologie).
- MESH :
- diagnostic : Séropositivité VIH.
- génétique : VIH-1 (Virus de l'Immunodéficience Humaine de type 1).
- immunologie : Antigènes du VIH, VIH-1 (Virus de l'Immunodéficience Humaine de type 1).
- normes : Techniques immunoenzymatiques, Tests sérologiques.
- épidémiologie : Séropositivité VIH.
- Affinité des anticorps, Calibrage, Humains, VIH-1 (Virus de l'Immunodéficience Humaine de type 1).
English descriptors
- KwdEn :
- MESH :
- chemical , immunology : HIV Antigens.
- classification : HIV-1.
- diagnosis : HIV Seropositivity.
- epidemiology : HIV Seropositivity.
- genetics : HIV-1.
- immunology : HIV-1.
- standards : Immunoenzyme Techniques, Serologic Tests.
- Antibody Affinity, Calibration, Humans.
Abstract
Mean duration of recent infection (MDRI) and misclassification of long-term HIV-1 infections, as proportion false recent (PFR), are critical parameters for laboratory-based assays for estimating HIV-1 incidence. Recent review of the data by us and others indicated that MDRI of LAg-Avidity EIA estimated previously required recalibration. We present here results of recalibration efforts using >250 seroconversion panels and multiple statistical methods to ensure accuracy and consensus.
DOI: 10.1371/journal.pone.0114947
PubMed: 25710171
Affiliations:
- Afrique du Sud, Ghana, Kenya, République populaire de Chine, Thaïlande, Viêt Nam, États-Unis
- Californie, Géorgie (États-Unis), Région du Grand Accra
- Accra, Pékin
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Le document en format XML
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Duong</name><affiliation wicri:level="2"><nlm:affiliation>International Laboratory Branch, Division of Global HIV/AIDS, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>International Laboratory Branch, Division of Global HIV/AIDS, Centers for Disease Control and Prevention, Atlanta, Georgia</wicri:regionArea><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Kassanjee, Reshma" sort="Kassanjee, Reshma" uniqKey="Kassanjee R" first="Reshma" last="Kassanjee">Reshma Kassanjee</name><affiliation wicri:level="1"><nlm:affiliation>The South African DST/NRF Centre of Excellence in Epidemiological Modelling and Analysis (SACEMA), University of Stellenbosch, Stellenbosch, South Africa; School of Computational and Applied Mathematics, University of the Witwatersrand, Johannesburg, South Africa.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>The South African DST/NRF Centre of Excellence in Epidemiological Modelling and Analysis (SACEMA), University of Stellenbosch, Stellenbosch, South Africa; 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Curlin</name><affiliation wicri:level="1"><nlm:affiliation>Thailand Ministry of Public Health-US CDC Collaboration, Bangkok, Thailand.</nlm:affiliation><country xml:lang="fr">Thaïlande</country><wicri:regionArea>Thailand Ministry of Public Health-US CDC Collaboration, Bangkok</wicri:regionArea><wicri:noRegion>Bangkok</wicri:noRegion></affiliation></author><author><name sortKey="Kittinunvorakoon, Chonticha" sort="Kittinunvorakoon, Chonticha" uniqKey="Kittinunvorakoon C" first="Chonticha" last="Kittinunvorakoon">Chonticha Kittinunvorakoon</name><affiliation wicri:level="1"><nlm:affiliation>Thailand Ministry of Public Health-US CDC Collaboration, Bangkok, Thailand.</nlm:affiliation><country xml:lang="fr">Thaïlande</country><wicri:regionArea>Thailand Ministry of Public Health-US CDC Collaboration, Bangkok</wicri:regionArea><wicri:noRegion>Bangkok</wicri:noRegion></affiliation></author><author><name sortKey="Raengsakulrach, Boonyos" sort="Raengsakulrach, Boonyos" uniqKey="Raengsakulrach B" first="Boonyos" last="Raengsakulrach">Boonyos Raengsakulrach</name><affiliation wicri:level="1"><nlm:affiliation>Thailand Ministry of Public Health-US CDC Collaboration, Bangkok, Thailand.</nlm:affiliation><country xml:lang="fr">Thaïlande</country><wicri:regionArea>Thailand Ministry of Public Health-US CDC Collaboration, Bangkok</wicri:regionArea><wicri:noRegion>Bangkok</wicri:noRegion></affiliation></author><author><name sortKey="Martin, Michael" sort="Martin, Michael" uniqKey="Martin M" first="Michael" last="Martin">Michael Martin</name><affiliation wicri:level="1"><nlm:affiliation>Thailand Ministry of Public Health-US CDC Collaboration, Bangkok, Thailand.</nlm:affiliation><country xml:lang="fr">Thaïlande</country><wicri:regionArea>Thailand Ministry of Public Health-US CDC Collaboration, Bangkok</wicri:regionArea><wicri:noRegion>Bangkok</wicri:noRegion></affiliation></author><author><name sortKey="Choopanya, Kachit" sort="Choopanya, Kachit" uniqKey="Choopanya K" first="Kachit" last="Choopanya">Kachit Choopanya</name><affiliation wicri:level="1"><nlm:affiliation>Thailand Ministry of Public Health-US CDC Collaboration, Bangkok, Thailand.</nlm:affiliation><country xml:lang="fr">Thaïlande</country><wicri:regionArea>Thailand Ministry of Public Health-US CDC Collaboration, Bangkok</wicri:regionArea><wicri:noRegion>Bangkok</wicri:noRegion></affiliation></author><author><name sortKey="Vanichseni, Suphak" sort="Vanichseni, Suphak" uniqKey="Vanichseni S" first="Suphak" last="Vanichseni">Suphak Vanichseni</name><affiliation wicri:level="1"><nlm:affiliation>Thailand Ministry of Public Health-US CDC Collaboration, Bangkok, Thailand.</nlm:affiliation><country xml:lang="fr">Thaïlande</country><wicri:regionArea>Thailand Ministry of Public Health-US CDC Collaboration, Bangkok</wicri:regionArea><wicri:noRegion>Bangkok</wicri:noRegion></affiliation></author><author><name sortKey="Jiang, Yan" sort="Jiang, Yan" uniqKey="Jiang Y" first="Yan" last="Jiang">Yan Jiang</name><affiliation wicri:level="3"><nlm:affiliation>National AIDS Reference Laboratory, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>National AIDS Reference Laboratory, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Qiu, Maofeng" sort="Qiu, Maofeng" uniqKey="Qiu M" first="Maofeng" last="Qiu">Maofeng Qiu</name><affiliation wicri:level="3"><nlm:affiliation>National AIDS Reference Laboratory, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>National AIDS Reference Laboratory, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Yu, Haiying" sort="Yu, Haiying" uniqKey="Yu H" first="Haiying" last="Yu">Haiying Yu</name><affiliation wicri:level="3"><nlm:affiliation>National AIDS Reference Laboratory, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>National AIDS Reference Laboratory, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Hao, Yan" sort="Hao, Yan" uniqKey="Hao Y" first="Yan" last="Hao">Yan Hao</name><affiliation wicri:level="3"><nlm:affiliation>National AIDS Reference Laboratory, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>National AIDS Reference Laboratory, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Shah, Neha" sort="Shah, Neha" uniqKey="Shah N" first="Neha" last="Shah">Neha Shah</name><affiliation wicri:level="2"><nlm:affiliation>California Department of Public Health, Richmond, California, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>California Department of Public Health, Richmond, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Le, Linh Vi" sort="Le, Linh Vi" uniqKey="Le L" first="Linh-Vi" last="Le">Linh-Vi Le</name><affiliation wicri:level="1"><nlm:affiliation>Division of Global HIV/AIDS, Centers for Disease Control and Prevention, Hanoi, Vietnam.</nlm:affiliation><country xml:lang="fr">Viêt Nam</country><wicri:regionArea>Division of Global HIV/AIDS, Centers for Disease Control and Prevention, Hanoi</wicri:regionArea><wicri:noRegion>Hanoi</wicri:noRegion></affiliation></author><author><name sortKey="Kim, Andrea A" sort="Kim, Andrea A" uniqKey="Kim A" first="Andrea A" last="Kim">Andrea A. Kim</name><affiliation wicri:level="1"><nlm:affiliation>CDC-Kenya, Nairobi, Kenya.</nlm:affiliation><country xml:lang="fr">Kenya</country><wicri:regionArea>CDC-Kenya, Nairobi</wicri:regionArea><wicri:noRegion>Nairobi</wicri:noRegion></affiliation></author><author><name sortKey="Nguyen, Tuan Anh" sort="Nguyen, Tuan Anh" uniqKey="Nguyen T" first="Tuan Anh" last="Nguyen">Tuan Anh Nguyen</name><affiliation wicri:level="1"><nlm:affiliation>National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.</nlm:affiliation><country xml:lang="fr">Viêt Nam</country><wicri:regionArea>National Institute of Hygiene and Epidemiology, Hanoi</wicri:regionArea><wicri:noRegion>Hanoi</wicri:noRegion></affiliation></author><author><name sortKey="Ampofo, William" sort="Ampofo, William" uniqKey="Ampofo W" first="William" last="Ampofo">William Ampofo</name><affiliation wicri:level="3"><nlm:affiliation>Noguchi Memorial Institute for Medical Research, Accra, Ghana.</nlm:affiliation><country xml:lang="fr">Ghana</country><wicri:regionArea>Noguchi Memorial Institute for Medical Research, Accra</wicri:regionArea><placeName><settlement type="city">Accra</settlement><region nuts="2">Région du Grand Accra</region></placeName></affiliation></author><author><name sortKey="Parekh, Bharat S" sort="Parekh, Bharat S" uniqKey="Parekh B" first="Bharat S" last="Parekh">Bharat S. Parekh</name><affiliation wicri:level="2"><nlm:affiliation>International Laboratory Branch, Division of Global HIV/AIDS, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>International Laboratory Branch, Division of Global HIV/AIDS, Centers for Disease Control and Prevention, Atlanta, Georgia</wicri:regionArea><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2015">2015</date><idno type="RBID">pubmed:25710171</idno><idno type="pmid">25710171</idno><idno type="doi">10.1371/journal.pone.0114947</idno><idno type="wicri:Area/PubMed/Corpus">000447</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000447</idno><idno type="wicri:Area/PubMed/Curation">000447</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000447</idno><idno type="wicri:Area/PubMed/Checkpoint">000447</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000447</idno><idno type="wicri:Area/Ncbi/Merge">000765</idno><idno type="wicri:Area/Ncbi/Curation">000765</idno><idno type="wicri:Area/Ncbi/Checkpoint">000765</idno><idno type="wicri:Area/Main/Merge">000280</idno><idno type="wicri:Area/Main/Curation">000280</idno><idno type="wicri:Area/Main/Exploration">000280</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Recalibration of the limiting antigen avidity EIA to determine mean duration of recent infection in divergent HIV-1 subtypes.</title><author><name sortKey="Duong, Yen T" sort="Duong, Yen T" uniqKey="Duong Y" first="Yen T" last="Duong">Yen T. Duong</name><affiliation wicri:level="2"><nlm:affiliation>International Laboratory Branch, Division of Global HIV/AIDS, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>International Laboratory Branch, Division of Global HIV/AIDS, Centers for Disease Control and Prevention, Atlanta, Georgia</wicri:regionArea><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Kassanjee, Reshma" sort="Kassanjee, Reshma" uniqKey="Kassanjee R" first="Reshma" last="Kassanjee">Reshma Kassanjee</name><affiliation wicri:level="1"><nlm:affiliation>The South African DST/NRF Centre of Excellence in Epidemiological Modelling and Analysis (SACEMA), University of Stellenbosch, Stellenbosch, South Africa; School of Computational and Applied Mathematics, University of the Witwatersrand, Johannesburg, South Africa.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>The South African DST/NRF Centre of Excellence in Epidemiological Modelling and Analysis (SACEMA), University of Stellenbosch, Stellenbosch, South Africa; School of Computational and Applied Mathematics, University of the Witwatersrand, Johannesburg</wicri:regionArea><wicri:noRegion>Johannesburg</wicri:noRegion></affiliation></author><author><name sortKey="Welte, Alex" sort="Welte, Alex" uniqKey="Welte A" first="Alex" last="Welte">Alex Welte</name><affiliation wicri:level="1"><nlm:affiliation>The South African DST/NRF Centre of Excellence in Epidemiological Modelling and Analysis (SACEMA), University of Stellenbosch, Stellenbosch, South Africa.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>The South African DST/NRF Centre of Excellence in Epidemiological Modelling and Analysis (SACEMA), University of Stellenbosch, Stellenbosch</wicri:regionArea><wicri:noRegion>Stellenbosch</wicri:noRegion></affiliation></author><author><name sortKey="Morgan, Meade" sort="Morgan, Meade" uniqKey="Morgan M" first="Meade" last="Morgan">Meade Morgan</name><affiliation wicri:level="2"><nlm:affiliation>Epidemiology and Strategic Information Branch, Division of Global HIV/AIDS, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Epidemiology and Strategic Information Branch, Division of Global HIV/AIDS, Centers for Disease Control and Prevention, Atlanta, Georgia</wicri:regionArea><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="De, Anindya" sort="De, Anindya" uniqKey="De A" first="Anindya" last="De">Anindya De</name><affiliation wicri:level="2"><nlm:affiliation>Epidemiology and Strategic Information Branch, Division of Global HIV/AIDS, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Epidemiology and Strategic Information Branch, Division of Global HIV/AIDS, Centers for Disease Control and Prevention, Atlanta, Georgia</wicri:regionArea><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Dobbs, Trudy" sort="Dobbs, Trudy" uniqKey="Dobbs T" first="Trudy" last="Dobbs">Trudy Dobbs</name><affiliation wicri:level="2"><nlm:affiliation>International Laboratory Branch, Division of Global HIV/AIDS, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>International Laboratory Branch, Division of Global HIV/AIDS, Centers for Disease Control and Prevention, Atlanta, Georgia</wicri:regionArea><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Rottinghaus, Erin" sort="Rottinghaus, Erin" uniqKey="Rottinghaus E" first="Erin" last="Rottinghaus">Erin Rottinghaus</name><affiliation wicri:level="2"><nlm:affiliation>International Laboratory Branch, Division of Global HIV/AIDS, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>International Laboratory Branch, Division of Global HIV/AIDS, Centers for Disease Control and Prevention, Atlanta, Georgia</wicri:regionArea><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Nkengasong, John" sort="Nkengasong, John" uniqKey="Nkengasong J" first="John" last="Nkengasong">John Nkengasong</name><affiliation wicri:level="2"><nlm:affiliation>International Laboratory Branch, Division of Global HIV/AIDS, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>International Laboratory Branch, Division of Global HIV/AIDS, Centers for Disease Control and Prevention, Atlanta, Georgia</wicri:regionArea><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Curlin, Marcel E" sort="Curlin, Marcel E" uniqKey="Curlin M" first="Marcel E" last="Curlin">Marcel E. Curlin</name><affiliation wicri:level="1"><nlm:affiliation>Thailand Ministry of Public Health-US CDC Collaboration, Bangkok, Thailand.</nlm:affiliation><country xml:lang="fr">Thaïlande</country><wicri:regionArea>Thailand Ministry of Public Health-US CDC Collaboration, Bangkok</wicri:regionArea><wicri:noRegion>Bangkok</wicri:noRegion></affiliation></author><author><name sortKey="Kittinunvorakoon, Chonticha" sort="Kittinunvorakoon, Chonticha" uniqKey="Kittinunvorakoon C" first="Chonticha" last="Kittinunvorakoon">Chonticha Kittinunvorakoon</name><affiliation wicri:level="1"><nlm:affiliation>Thailand Ministry of Public Health-US CDC Collaboration, Bangkok, Thailand.</nlm:affiliation><country xml:lang="fr">Thaïlande</country><wicri:regionArea>Thailand Ministry of Public Health-US CDC Collaboration, Bangkok</wicri:regionArea><wicri:noRegion>Bangkok</wicri:noRegion></affiliation></author><author><name sortKey="Raengsakulrach, Boonyos" sort="Raengsakulrach, Boonyos" uniqKey="Raengsakulrach B" first="Boonyos" last="Raengsakulrach">Boonyos Raengsakulrach</name><affiliation wicri:level="1"><nlm:affiliation>Thailand Ministry of Public Health-US CDC Collaboration, Bangkok, Thailand.</nlm:affiliation><country xml:lang="fr">Thaïlande</country><wicri:regionArea>Thailand Ministry of Public Health-US CDC Collaboration, Bangkok</wicri:regionArea><wicri:noRegion>Bangkok</wicri:noRegion></affiliation></author><author><name sortKey="Martin, Michael" sort="Martin, Michael" uniqKey="Martin M" first="Michael" last="Martin">Michael Martin</name><affiliation wicri:level="1"><nlm:affiliation>Thailand Ministry of Public Health-US CDC Collaboration, Bangkok, Thailand.</nlm:affiliation><country xml:lang="fr">Thaïlande</country><wicri:regionArea>Thailand Ministry of Public Health-US CDC Collaboration, Bangkok</wicri:regionArea><wicri:noRegion>Bangkok</wicri:noRegion></affiliation></author><author><name sortKey="Choopanya, Kachit" sort="Choopanya, Kachit" uniqKey="Choopanya K" first="Kachit" last="Choopanya">Kachit Choopanya</name><affiliation wicri:level="1"><nlm:affiliation>Thailand Ministry of Public Health-US CDC Collaboration, Bangkok, Thailand.</nlm:affiliation><country xml:lang="fr">Thaïlande</country><wicri:regionArea>Thailand Ministry of Public Health-US CDC Collaboration, Bangkok</wicri:regionArea><wicri:noRegion>Bangkok</wicri:noRegion></affiliation></author><author><name sortKey="Vanichseni, Suphak" sort="Vanichseni, Suphak" uniqKey="Vanichseni S" first="Suphak" last="Vanichseni">Suphak Vanichseni</name><affiliation wicri:level="1"><nlm:affiliation>Thailand Ministry of Public Health-US CDC Collaboration, Bangkok, Thailand.</nlm:affiliation><country xml:lang="fr">Thaïlande</country><wicri:regionArea>Thailand Ministry of Public Health-US CDC Collaboration, Bangkok</wicri:regionArea><wicri:noRegion>Bangkok</wicri:noRegion></affiliation></author><author><name sortKey="Jiang, Yan" sort="Jiang, Yan" uniqKey="Jiang Y" first="Yan" last="Jiang">Yan Jiang</name><affiliation wicri:level="3"><nlm:affiliation>National AIDS Reference Laboratory, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>National AIDS Reference Laboratory, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Qiu, Maofeng" sort="Qiu, Maofeng" uniqKey="Qiu M" first="Maofeng" last="Qiu">Maofeng Qiu</name><affiliation wicri:level="3"><nlm:affiliation>National AIDS Reference Laboratory, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>National AIDS Reference Laboratory, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Yu, Haiying" sort="Yu, Haiying" uniqKey="Yu H" first="Haiying" last="Yu">Haiying Yu</name><affiliation wicri:level="3"><nlm:affiliation>National AIDS Reference Laboratory, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>National AIDS Reference Laboratory, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Hao, Yan" sort="Hao, Yan" uniqKey="Hao Y" first="Yan" last="Hao">Yan Hao</name><affiliation wicri:level="3"><nlm:affiliation>National AIDS Reference Laboratory, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>National AIDS Reference Laboratory, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Shah, Neha" sort="Shah, Neha" uniqKey="Shah N" first="Neha" last="Shah">Neha Shah</name><affiliation wicri:level="2"><nlm:affiliation>California Department of Public Health, Richmond, California, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>California Department of Public Health, Richmond, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Le, Linh Vi" sort="Le, Linh Vi" uniqKey="Le L" first="Linh-Vi" last="Le">Linh-Vi Le</name><affiliation wicri:level="1"><nlm:affiliation>Division of Global HIV/AIDS, Centers for Disease Control and Prevention, Hanoi, Vietnam.</nlm:affiliation><country xml:lang="fr">Viêt Nam</country><wicri:regionArea>Division of Global HIV/AIDS, Centers for Disease Control and Prevention, Hanoi</wicri:regionArea><wicri:noRegion>Hanoi</wicri:noRegion></affiliation></author><author><name sortKey="Kim, Andrea A" sort="Kim, Andrea A" uniqKey="Kim A" first="Andrea A" last="Kim">Andrea A. Kim</name><affiliation wicri:level="1"><nlm:affiliation>CDC-Kenya, Nairobi, Kenya.</nlm:affiliation><country xml:lang="fr">Kenya</country><wicri:regionArea>CDC-Kenya, Nairobi</wicri:regionArea><wicri:noRegion>Nairobi</wicri:noRegion></affiliation></author><author><name sortKey="Nguyen, Tuan Anh" sort="Nguyen, Tuan Anh" uniqKey="Nguyen T" first="Tuan Anh" last="Nguyen">Tuan Anh Nguyen</name><affiliation wicri:level="1"><nlm:affiliation>National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.</nlm:affiliation><country xml:lang="fr">Viêt Nam</country><wicri:regionArea>National Institute of Hygiene and Epidemiology, Hanoi</wicri:regionArea><wicri:noRegion>Hanoi</wicri:noRegion></affiliation></author><author><name sortKey="Ampofo, William" sort="Ampofo, William" uniqKey="Ampofo W" first="William" last="Ampofo">William Ampofo</name><affiliation wicri:level="3"><nlm:affiliation>Noguchi Memorial Institute for Medical Research, Accra, Ghana.</nlm:affiliation><country xml:lang="fr">Ghana</country><wicri:regionArea>Noguchi Memorial Institute for Medical Research, Accra</wicri:regionArea><placeName><settlement type="city">Accra</settlement><region nuts="2">Région du Grand Accra</region></placeName></affiliation></author><author><name sortKey="Parekh, Bharat S" sort="Parekh, Bharat S" uniqKey="Parekh B" first="Bharat S" last="Parekh">Bharat S. Parekh</name><affiliation wicri:level="2"><nlm:affiliation>International Laboratory Branch, Division of Global HIV/AIDS, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>International Laboratory Branch, Division of Global HIV/AIDS, Centers for Disease Control and Prevention, Atlanta, Georgia</wicri:regionArea><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author></analytic><series><title level="j">PloS one</title><idno type="eISSN">1932-6203</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antibody Affinity</term><term>Calibration</term><term>HIV Antigens (immunology)</term><term>HIV Seropositivity (diagnosis)</term><term>HIV Seropositivity (epidemiology)</term><term>HIV-1 (classification)</term><term>HIV-1 (genetics)</term><term>HIV-1 (immunology)</term><term>Humans</term><term>Immunoenzyme Techniques (standards)</term><term>Serologic Tests (standards)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Affinité des anticorps</term><term>Antigènes du VIH (immunologie)</term><term>Calibrage</term><term>Humains</term><term>Séropositivité VIH (diagnostic)</term><term>Séropositivité VIH (épidémiologie)</term><term>Techniques immunoenzymatiques (normes)</term><term>Tests sérologiques (normes)</term><term>VIH-1 (Virus de l'Immunodéficience Humaine de type 1) ()</term><term>VIH-1 (Virus de l'Immunodéficience Humaine de type 1) (génétique)</term><term>VIH-1 (Virus de l'Immunodéficience Humaine de type 1) (immunologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>HIV Antigens</term></keywords><keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>HIV-1</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>HIV Seropositivity</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Séropositivité VIH</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>HIV Seropositivity</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>HIV-1</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>VIH-1 (Virus de l'Immunodéficience Humaine de type 1)</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Antigènes du VIH</term><term>VIH-1 (Virus de l'Immunodéficience Humaine de type 1)</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>HIV-1</term></keywords><keywords scheme="MESH" qualifier="normes" xml:lang="fr"><term>Techniques immunoenzymatiques</term><term>Tests sérologiques</term></keywords><keywords scheme="MESH" qualifier="standards" xml:lang="en"><term>Immunoenzyme Techniques</term><term>Serologic Tests</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Séropositivité VIH</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Antibody Affinity</term><term>Calibration</term><term>Humans</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Affinité des anticorps</term><term>Calibrage</term><term>Humains</term><term>VIH-1 (Virus de l'Immunodéficience Humaine de type 1)</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Mean duration of recent infection (MDRI) and misclassification of long-term HIV-1 infections, as proportion false recent (PFR), are critical parameters for laboratory-based assays for estimating HIV-1 incidence. Recent review of the data by us and others indicated that MDRI of LAg-Avidity EIA estimated previously required recalibration. We present here results of recalibration efforts using >250 seroconversion panels and multiple statistical methods to ensure accuracy and consensus.</div></front></TEI><affiliations><list><country><li>Afrique du Sud</li><li>Ghana</li><li>Kenya</li><li>République populaire de Chine</li><li>Thaïlande</li><li>Viêt Nam</li><li>États-Unis</li></country><region><li>Californie</li><li>Géorgie (États-Unis)</li><li>Région du Grand Accra</li></region><settlement><li>Accra</li><li>Pékin</li></settlement></list><tree><country name="États-Unis"><region name="Géorgie (États-Unis)"><name sortKey="Duong, Yen T" sort="Duong, Yen T" uniqKey="Duong Y" first="Yen T" last="Duong">Yen T. Duong</name></region><name sortKey="De, Anindya" sort="De, Anindya" uniqKey="De A" first="Anindya" last="De">Anindya De</name><name sortKey="Dobbs, Trudy" sort="Dobbs, Trudy" uniqKey="Dobbs T" first="Trudy" last="Dobbs">Trudy Dobbs</name><name sortKey="Morgan, Meade" sort="Morgan, Meade" uniqKey="Morgan M" first="Meade" last="Morgan">Meade Morgan</name><name sortKey="Nkengasong, John" sort="Nkengasong, John" uniqKey="Nkengasong J" first="John" last="Nkengasong">John Nkengasong</name><name sortKey="Parekh, Bharat S" sort="Parekh, Bharat S" uniqKey="Parekh B" first="Bharat S" last="Parekh">Bharat S. Parekh</name><name sortKey="Rottinghaus, Erin" sort="Rottinghaus, Erin" uniqKey="Rottinghaus E" first="Erin" last="Rottinghaus">Erin Rottinghaus</name><name sortKey="Shah, Neha" sort="Shah, Neha" uniqKey="Shah N" first="Neha" last="Shah">Neha Shah</name></country><country name="Afrique du Sud"><noRegion><name sortKey="Kassanjee, Reshma" sort="Kassanjee, Reshma" uniqKey="Kassanjee R" first="Reshma" last="Kassanjee">Reshma Kassanjee</name></noRegion><name sortKey="Welte, Alex" sort="Welte, Alex" uniqKey="Welte A" first="Alex" last="Welte">Alex Welte</name></country><country name="Thaïlande"><noRegion><name sortKey="Curlin, Marcel E" sort="Curlin, Marcel E" uniqKey="Curlin M" first="Marcel E" last="Curlin">Marcel E. Curlin</name></noRegion><name sortKey="Choopanya, Kachit" sort="Choopanya, Kachit" uniqKey="Choopanya K" first="Kachit" last="Choopanya">Kachit Choopanya</name><name sortKey="Kittinunvorakoon, Chonticha" sort="Kittinunvorakoon, Chonticha" uniqKey="Kittinunvorakoon C" first="Chonticha" last="Kittinunvorakoon">Chonticha Kittinunvorakoon</name><name sortKey="Martin, Michael" sort="Martin, Michael" uniqKey="Martin M" first="Michael" last="Martin">Michael Martin</name><name sortKey="Raengsakulrach, Boonyos" sort="Raengsakulrach, Boonyos" uniqKey="Raengsakulrach B" first="Boonyos" last="Raengsakulrach">Boonyos Raengsakulrach</name><name sortKey="Vanichseni, Suphak" sort="Vanichseni, Suphak" uniqKey="Vanichseni S" first="Suphak" last="Vanichseni">Suphak Vanichseni</name></country><country name="République populaire de Chine"><noRegion><name sortKey="Jiang, Yan" sort="Jiang, Yan" uniqKey="Jiang Y" first="Yan" last="Jiang">Yan Jiang</name></noRegion><name sortKey="Hao, Yan" sort="Hao, Yan" uniqKey="Hao Y" first="Yan" last="Hao">Yan Hao</name><name sortKey="Qiu, Maofeng" sort="Qiu, Maofeng" uniqKey="Qiu M" first="Maofeng" last="Qiu">Maofeng Qiu</name><name sortKey="Yu, Haiying" sort="Yu, Haiying" uniqKey="Yu H" first="Haiying" last="Yu">Haiying Yu</name></country><country name="Viêt Nam"><noRegion><name sortKey="Le, Linh Vi" sort="Le, Linh Vi" uniqKey="Le L" first="Linh-Vi" last="Le">Linh-Vi Le</name></noRegion><name sortKey="Nguyen, Tuan Anh" sort="Nguyen, Tuan Anh" uniqKey="Nguyen T" first="Tuan Anh" last="Nguyen">Tuan Anh Nguyen</name></country><country name="Kenya"><noRegion><name sortKey="Kim, Andrea A" sort="Kim, Andrea A" uniqKey="Kim A" first="Andrea A" last="Kim">Andrea A. Kim</name></noRegion></country><country name="Ghana"><region name="Région du Grand Accra"><name sortKey="Ampofo, William" sort="Ampofo, William" uniqKey="Ampofo W" first="William" last="Ampofo">William Ampofo</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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